Adamax is a synthetic ACTH(4-10) analog peptide developed as a structurally modified derivative of Semax. The Semax core sequence (Met-Glu-His-Phe-Pro-Gly-Pro) is acetylated at the N-terminus and incorporates an adamantyl group — modifications that extend plasma half-life from minutes to several hours and improve blood-brain barrier penetration relative to unmodified Semax. Supplied as a sterile lyophilized powder with documented purity specifications. Suitable for in vitro investigations of BDNF/TrkB signaling, MC4 receptor pharmacology, and CNS neuropeptide structure-activity research.
- Purity: ≥99% (HPLC)
- Form: Sterile lyophilized powder
- Storage: -20°C, protect from light and moisture
- Reconstitution: Bacteriostatic water (BAC water) or appropriate buffer
- Stability: 24+ months as supplied; reconstituted solutions stored at 2–8°C and used within 30 days
- Sequence: N-Acetyl-Semax (Ac-MEHFPGP) with adamantyl modification
Supplied as a lyophilized powder and sealed against light and moisture — shelf-stable, no cold chain required. Every lot is assayed by an independent laboratory and the certificate is published before the compound is listed. Strictly for in-vitro laboratory research.
Research applications
- BDNF expression and TrkB receptor sensitization studies in hippocampal and cortical models
- MC4 receptor pharmacology and ACTH(4-10) analog signaling research
- Long-term potentiation (LTP) and synaptic plasticity investigation
- Cognitive function and learning/memory research models
- Neuroprotection and oxidative stress response studies
- Extended-half-life CNS peptide pharmacokinetic characterization
Storage & handling
Handle under aseptic conditions in accordance with laboratory safety protocols. Lyophilized material should be stored at -20°C protected from light and moisture. Reconstitute by injecting bacteriostatic water (BAC water) slowly along the vial wall and swirling gently — do not vortex. Once reconstituted, store at 2–8°C and use within 30 days; aliquot to avoid repeated freeze-thaw cycles. Refer to the Certificate of Analysis (CoA) for batch-specific handling recommendations. For laboratory research use only — not for human consumption, veterinary use, or food and drug applications.
Research notes
- What is the intended use of this compound? For laboratory research use only. Not for human or veterinary use.
- Is a Certificate of Analysis available? Yes, each lot is supplied with a CoA documenting purity and identity confirmation by independent third-party HPLC and mass spectrometry.
- What reconstitution buffer is recommended? Bacteriostatic water (BAC water) is the most commonly referenced solvent in published Semax-family research protocols. Sterile water or appropriate buffer may also be used depending on the experimental design.
- How does Adamax differ from Semax? Adamax adds N-acetylation and an adamantyl modification to the Semax (MEHFPGP) core, extending plasma half-life from minutes to several hours and improving blood-brain barrier penetration in research models.
- Can this be used in cell culture experiments? Yes, when properly reconstituted and diluted under sterile conditions for in vitro applications.
Specifications
FormLyophilized powderPurity≥99% (HPLC verified)Presentation10mgStorageStore lyophilized at −20°C; protect from light.Catalog #NL-36140
For research use only. Not for human or veterinary use. Not a drug, food, or supplement.
Tested before it’s listed
Certificate of AnalysisLOT · NLL-2825133CompoundAdamaxAssay (HPLC)≥99%Identity (MS)ConfirmedAppearanceWhite lyophilateEndotoxinTested
Each batch is independently assayed by reverse-phase HPLC for purity and confirmed by mass spectrometry for identity. The exact paperwork for the exact vial ships with your order and lives in your account.
HPLC purity≥99% (HPLC verified)Mass-spec identityConfirmedLot archivalUnique lot ID per batch View COA →
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